%20%D0%B1%D0%B5%D0%B7%20%D0%BE%D1%87%D0%B8%D1%81%D1%82%D0%BA%D0%B8%20%E2%80%94%20%D0%BA%D0%BE%D0%BF%D0%B8%D1%8F.jpg "Chemists Simplify Synthesis of Drugs Involving Amide Groups")
Chemists Simplify Synthesis of Drugs Involving Amide Groups
Chemists from HSE University and the Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences (INEOS RAS) have developed a new method for synthesising amides, essential compounds in drug production. Using a ruthenium catalyst and carbon monoxide under precisely controlled reaction conditions, they successfully obtained the target product without by-products or complex purification steps. The method has already been tested for synthesising a key component of Vorinostat, a drug used to treat T-cell lymphoma. This approach could lower the cost of the drug by orders of magnitude. The paper has been published in the Journal of Catalysis. The study was supported by the Russian Science Foundation.
Implementation of Principles of Sustainable Development Attracts More Investments
Economists from HSE and RUDN University have analysed issues related to corporate digital transformation processes. The introduction of digital solutions into corporate operations reduces the number of patents in the field of green technologies by 4% and creates additional financial difficulties. However, if a company focuses on sustainable development and increases its rating in environmental, social, and governance performance (ESG), the negative effects decrease. Moreover, when the ESG rating is high, digitalisation can even increase the number of patents by 2%. The article was published in Sustainability.
Russian Scientists Develop New Compound for Treating Aggressive Tumours
A team of Russian researchers has synthesised a novel compound for boron neutron capture therapy (BNCT), a treatment for advanced cancer that uses the boron-10 isotope. The compound exhibits low toxicity, excellent water solubility, and eliminates the need for administering large volumes. Most importantly, the active substance reaches the tumour with minimal impact on healthy tissues. The study was published in the International Journal of Molecular Sciences shortly before World Cancer Day, observed annually on February 4.
HSE Scientists Take Important Step Forward in Development of 6G Communication Technologies
Researchers at HSE MIEM have successfully demonstrated the effective operation of a 6G wireless communication channel at sub-THz frequencies. The device transmits data at 12 Gbps and maintains signal stability by automatically switching when blocked. These metrics comply with international 6G standards. An article published on arXiv, an open-access electronic repository, provides a description of certain elements of the system.
HSE Researchers Adapt Popular Usability Test
A team of researchers from the HSE Faculty of Social Sciences has adapted the widely used System Usability Scale (SUS) for Russian-speaking users, testing the adaptation on a sample of 657 participants. A validity test confirmed that the translated questionnaire maintains its structure and reliability, enabling an accurate assessment of system usability. The final adapted version of the SUS questionnaire can be used in both research and interface design practice. The paper has been published in Psychological Studies.